For example, the epigenetic factor protein arginine methyltransferase 5 (PRMT5) silenced the expression of the tumour suppressor F‐box/WD repeat‐containing protein 7 (FBW7) epigenetically, leading to upregulation of cMyc, and subsequently enhanced the aerobic glycolysis in pancreatic cancer cells and its proliferation.53 This evidence concerns the gene MYC and familial pancreatic carcinoma.