Similarly, the anti-proliferative effects of the member of the proteasome PSMB5 and the transcription factor E4F1 have been widely studied in triple negative breast cancer and myeloid leukaemia cells, respectively  [56, 57], whereas their potential links with BET inhibition as well as their wider roles in OC are largely unknown. This evidence concerns the gene PSMB5 and triple-negative breast carcinoma.