However, neutropenia is commonly associated with variants in other GINS subunits, GINS1 and GINS4 [71, 72], and in at least some individuals with a biallelic variant in the functionally related subunit of the MCM complex, MCM4, but not GINS2, GINS3 or MCM3, MCM5 or MCM7 [73]. This evidence concerns the gene GINS3 and Decreased total neutrophil count.