Although several bacterial pathogens have been shown to impact histone acetylation/deacetylation during infection by acting on expression of eukaryotic HDACs or their localization12, until now only the Neisseria gonorrhoeae Gc-HDAC protein has been shown to induce an enrichment of H3K9ac, in particular at the promoters of pro-inflammatory genes30. This evidence concerns the gene HDAC9 and infection.