To further explore the role of KAT7 during L. pneumophila infection and the synergistic activities of LphD and RomA, we quantified the levels of H3K14 methylation during infection with L. pneumophila wild-type or the ∆lphD mutant strain by pre-treating the cells with a KAT7 specific inhibitor (WM-3835) (Fig. 6D). Here, KAT7 is linked to infection.