In further analysis when the cohort was segregated into those with mild (F0–1) versus advanced fibrosis (F2–4), carriage of DIO2 rs225014 TT and rs225017 AA, and PPARG rs10865710 CC genotypes were associated with a significantly increased risk of advanced fibrosis, independent of age and gender (Table S1). Here, DIO2 is linked to fibrosis.