Furthermore, we analyzed the prognostic value of CYP1B1 using the GEPIA database (http://gepia.cancer-pku.cn/index.html), and we found that high expression of CYP1B1 levels were significantly associated with poor overall survival for colon adenocarcinoma (COAD) patients (Fig. 5D). Here, CYP1B1 is linked to colon adenocarcinoma.