As a result, 19 genes, including CDCA5, CENPF, CENPW, CDCA8, SPC25, CDKN3, CENPA, BUB1, DLGAP5, IGSF3, HMMR, TOP2A, RAD54L, TTK, GINS1, PTTG1, ETV4, GINS2, and PKMYT1 were found to be independent prognostic biomarkers in HCC (Supplementary Table 8 and Supplementary Figure 3). Here, BUB1 is linked to hepatocellular carcinoma.