TTR and amyloidosis: The overall 20-year survival after transplantation was 55.3%, and independent risk factors for good prognosis were: early-onset, Val30Met mutation, modified BMI before transplant, and a short disease duration.92However, a liver transplant does not interfere with eye or central nervous system amyloid deposition, as the retina and the choroid plexus continue secreting mutated TTR.66, 93Transplantation of livers from ATTRv-PN donors have been considered when the prospective recipients with other liver diseases would otherwise have a long wait or are seeking palliation rather than long-term cure.