PIK3C2A and peripheral neuropathy: Creatine phosphokinase (CPK) is usually normal and the pattern of weakness is proximal and symmetric lower limb predominant weakness.61Hereditary ATTR patients with nerve and muscle involvement can present with distal weakness and sensory deficits from the peripheral neuropathy and proximal weakness from the myopathy, mimicking chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).