Zhou et al. demonstrated that hsa_circ_0001666 functions as a tumor suppressor by directly binding miR‐576‐5p and lessening its inhibitory effect on the target gene Pcdh10, thereby inhibiting cell proliferation, metastasis, EMT progression and stemness as well as triggering apoptosis of CRC cells (Zhou et al. 2021). This evidence concerns the gene PCDH10 and colorectal carcinoma.