PCDH10 and Menkes disease: As aforementioned, deletion of Pcdh10 in mice does not affect the growth of striatal and nigrostriatal axons, but rather leads to defects in development of excitatory synapses in the dorsal basolateral nucleus of the amygdala, reduces anxiety, and causes fear and stress in ASD, OCD and MD (Hoshina et al. 2022).