For example, using MSP qPCR method, Pimson and colleagues demonstrated that Pcdh10 promoter methylation was detected in 94.06% of plasma DNA from gastric cancer patients whereas it was found in only 2.97% of matched controls, serving as a reliable non-invasive diagnostic indicator for GC (Pimson et al. 2016). Here, PCDH10 is linked to gastric cancer.