PCDH10 and neoplasm: Additionally, Pcdh10 is a newly discovered tumor suppressor gene which is downregulated by hypermethylation or genetic deletion in various malignant tumors, and is linked to the occurrence, proliferation, invasion and metastasis of tumors (Zhong et al. 2013; Qiu et al. 2016; Yang et al. 2016, 2022).