NR1H4 and infection: Following infection of naive HuH7.5-NTCP cells with viruses produced in dHepaRG cells treated with 6-ECDCA and tropifexor, a decrease of intracellular HDV RNAs by more than 95% was also observed, indicating that the specific infectivity of secreted HDV particles was affected by all 3 FXR ligands used in this study (Figure S10A, B, http://links.lww.com/HC9/A176).