Hence, the IHC and BLI results suggest that the difference in survival time between mice bearing U251 shControl and shNSUN5‐B tumors is not caused by the tumor mass, but likely due to the more migratory and invasive phenotype of U251 shControl cells, which is supported by our in vitro migration assays where knockdown of NSUN5 decreased migration of U251 cells (Fig. 5D). Here, NSUN5 is linked to neoplasm.