In LUAD, we found that METTL3 levels of tumor tissue at stage N0-N3 were significantly higher than those of normal tissue; similarly, in LUSC, METTL3 levels of tumor tissues at stage N0-N2 were significantly higher than those of normal tissue; however, there were no significant differences in METTL3 expression between stage N0 and N1-N2, suggesting that there was no correlation between METTL3 and nodal metastatic status (Figure 3J). The gene discussed is METTL3; the disease is neoplasm.