RAC3 and neoplasm: We found that RAC3 levels of tumor tissue at stage N0-N2 were higher than those of normal tissue in LUAD; similarly, RAC3 levels of tumor tissue at stage N0-N3 were significantly higher than those of normal tissue in LUSC; however, there were no significant differences in RAC3 levels of tumor tissue between stage N0 and N1-N2, suggesting that RAC3 did not correlate with nodal metastatic status (Figure 5K).