IFNG and neoplasm: Given that IFNγ has been shown to inhibit the fibroblast-diminished nuclear accumulation of platinum via altering glutathione and cysteine metabolism in fibroblasts 47, we speculate that the simultaneous injection of anti-IFNγ and cisplatin may inhibit the entry of cisplatin into tumour cells or promote cisplatin pumping, thereby inducing a resistance to chemotherapy.