In line with a similar lung bacterial burden, clodronate-treatment did not appear to affect the host inflammatory response following infection with W42Phago-Res, as no differences were observed in the number of monocytes and neutrophils in the BAL, lung MPO activity, and the levels of TNF, IL-1β, IL-12p40, IL-17A, CXCL1, and CCL5 in the lungs of vehicle- and clodronate-treated mice infected with W42Phago-Res (Figures 4C–F). The gene discussed is CXCL1; the disease is infection.