PDLIM7 and nasopharyngeal carcinoma: In addition, EBV-infection encoded oncoproteins such as LMP1, LMP2 and EBNA1 or their interactions with the TME includes immune cells and rodent fibroblasts have been proved to directly impact morphological and phenotypic alterations in epithelial cells, and the malignant progression or therapy response of NPC 22-25.