For example, lasmacytoid dendritic cells (pDCs), CLEC9A+ DCs, natural killer (NK) cells, and plasma cells were significantly associated with improved survival outcomes in NPC, whereas enrichment of M2-polarized macrophages and LAMP3+ dendritic cells leads to immunotolerance, promoting tumor progression of NPC. Here, LAMP3 is linked to nasopharyngeal carcinoma.