LAMB2 and retinal degeneration: Consistent with RNA-Seq screening, immunofluorescence staining showed that ECM components such as chondroitin sulfate (Figure 7F, G), fibronectin (Figure 7H, I), collagen I (Figure 7J, K) and laminin (Figure 7L, M) increased significantly during retinal degeneration compared to the c57 group.