Owing to previous analysis and experiments, we hypothesized a positive correlation between AhR and SLC7A11. To clarify this relationship, we detected the SLC7A11 protein level (by immunoblot) in lung cancer cell lines after overexpressing and knocking down AhR. The SLC7A11 protein level increased in the AhR overexpression cells (Fig. 5A) and decreased in the AhR knockdown cells (Fig. 5B). The gene discussed is SLC7A11; the disease is lung carcinoma.