Therefore, we performed a preliminarily ferroptosis-related gene expression analysis in lung ADC cells, finding Significant differential SLC7A11 expression after treating the cells with an AhR agonist and antagonist (Fig. 4B), suggesting that AhR may be related to SLC7A11.Furthermore, in order to explore the relationship between AhR and SLC7A11,we used the University of California Santa Cruz Genome Browser database and bioinformatics analyses showed that there might be AhR binding sites in the promoter region of SLC7A11 (Fig. 4C). Here, SLC7A11 is linked to AIDS dementia complex.