CD274 and colon adenocarcinoma: As the expressions of MCU complex members were associated with the immune cell infiltration, and the expressions of immune checkpoint molecules, especially PD-1 (programmed cell death 1, also named as PDCD1), PD-L1 (programmed cell death ligand 1, also named as CD274) and CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), were related with the responses to immunotherapy in COAD, we explored the correlationship between the expressions of MCU complex members and the immune checkpoint molecules.