BMI, body mass index; PAI-1, plasminogen activator inhibitor-1; MCP-1, monocyte chemoattractant protein-1; RETN, resistin; GIANT, Genetic Investigation of ANthropometric Traits; SCALLOP, Systematic and Combined AnaLysis of Olink proteins; VTE, venous thromboembolism; DVT, deep vein thrombosis; PE, pulmonary embolism. The gene discussed is SERPINE1; the disease is venous thromboembolism.