Given that the conclusion regarding the positive contribution of MCP-1 in the process of venous thrombus dissolution is derived from in vitro experiments and the association of MCP-1 with an elevated risk of cardiovascular embolic events is supported by higher quality studies, further research with robust evidence is warranted to establish the precise role played by MCP-1 in venous thromboembolism. This evidence concerns the gene CCL2 and venous thromboembolism.