SLC9A1 and type 2 diabetes mellitus: Jiang et al. [162] reported that in T1DM or T2DM and myocardial infarction, cardiomyocyte survival benefitted from the inhibition of enhanced autophagy by empagliflozin, which depended on the downregulation of NHE1 and NHE1-related genes that induce autophagy, such as Beclin 1 and autophagy-related protein 5.