RAG1 and colitis: Further, we transferred CD3+ T cells isolated from CarinhKO mice and their WT littermate controls into Rag1-deficient mice, and saw that these Carinh-deficient T cell-reconstituted mice were not susceptible to DSS-induced colitis (Supplementary information, Fig. S5), suggesting that the expression of Carinh in T cells was not required for the DSS phenotype.