DNMT3A and neoplasm: Silencing Dnmt1 did not impact the expression of Dnmt3a/3b, but approximated the effect of 5-Aza resulting in an ~2–4-fold increase in TNFα-stimulated Icam1, Vcam1, and Esel and ~25–100-fold increases in Cxcl9/10/11 which are important chemo-attractants for guiding CXCR3+ T-cells towards the tumor microenvironment (Supplementary Fig. 7b, Fig. 2a, b).