The long-stranded noncoding RNA of IGFL2 regulates the Wnt/β-catenin signaling pathway by increasing SATB1 expression to promote cancer development33, and in the results of GSEA enrichment analysis, we identified a significant enrichment of IGFL2 in the Wnt signaling pathway in thyroid cancer. This evidence concerns the gene SATB1 and thyroid gland carcinoma.