Since some cancers lacked normal tissue controls, we obtained basic information from the TCGA database and supplemented the normal tissue controls from the GTEx database, which showed (Fig. 1) that, in addition to the above cancers, the expression of ACC, CESC, DLBC, LAML, LGG, OV, PAAD, READ, TGCT, THYM and UCS differed significantly, suggesting that IGFL2 may be a participant in oncogenic events. The gene discussed is IGFL2; the disease is cancer.