MAPK8 and epilepsy: Other signaling cascades associated with tau and/or amyloid dysregulation include cyclin‐dependent kinase 5 (CDK5),45, 48 glycogen synthase kinase‐3β pathways (GSK‐3β),45, 48 protein phosphatase 2A (PP2A) signaling49 as well as Wingless/Integrated (Wnt), mitogen‐activated protein kinase (MAPK), and c‐Jun N‐terminal kinase (JNK) signaling, which are known to be altered in epilepsy.45, 48, 49, 51, 52, 53, 54