RHOA and hepatocellular carcinoma: Interestingly, the endothelium formed on HCC gels showed the strongest barrier to extravasation (49% decrease in extravasation efficiency compared to control, p‐value = 0.006, Figure4a,b), while TCs had the highest tendency to extravasate in RhoA depleted endothelium (2‐fold increase compared to control, p‐value = 0.0006, Figure 4a,b).