The tissue immuno-fluorescence images, Figs. 1H and S1A, show that YME1L protein (green fluorescence) is co-localized with the mitochondrial marker MitoTracker (red fluorescence) in both glioma slides and the adjacent normal brain slides of two representative glioma patients (Patients 3 and 4). This evidence concerns the gene YME1L1 and glioma.