YME1L1 and central nervous system cancer: To silence YME1L expression, the P1 primary human glioma cells (Liu et al., 2018; Wang et al., 2021) were individually transduced with two different lentiviral YME1L small hairpin RNA (shRNA) (lv-shYME1L-seq1 and lv-shYME1L-seq2, with different sequences).