Expression of the IFN signaling pathway in satellite cells has been previously described in patients with dermatomyositis (DM) and polymyositis, demonstrating the capacity of muscle to regulate this pathway (Greenberg et al., 2005; Salajegheh et al., 2010; Suárez-Calvet et al., 2014). This evidence concerns the gene IFNA1 and polymyositis.