Patients carrying FKBP5 rs4713916A or rs6926133A had greater depression scores (Z = –2.003, p = 0.0459 and Z = –2.108, p = 0.0353, respectively), suggesting that those SNPs may be risk alleles for the development of severe DD (Figures 3A, B). The gene discussed is FKBP5; the disease is depressive disorder.