In addition, other biomarkers such as serum fatty acid binding protein 4 (FABP4) (Li et al., 2019), serum CXCL12 levels (Gu et al., 2016), interleukin-37 (Zhang et al., 2021), and cystatin C (Liu et al., 2021) have been reported to be associated with stroke recurrence. This evidence concerns the gene CXCL12 and stroke disorder.