In ALI rats, it was discovered that α-MG therapy improved histological conditions (reduced interalveolar septal thickening, alveolar hemorrhage, and cells infiltration), lowered leucocyte counts, declined oxidative stress (a little recovery in superoxide dismutase (SOD) activity and reversed the elevation of malondialdehyde (MDA)), and decreased TNF-α levels. Here, AMELX is linked to acute respiratory distress syndrome.