Adipokines play an important role in the pathogenesis of DM which is related to adiposity. Adipose tissue has been identified as an endocrine organ secreting adipokines involved in metabolic and inflammatory pathways [11]. ZAGP is a novel adipokine; its expression in adipose tissue positively correlates with adiponectin expression [12,13]. The gene discussed is ADIPOQ; the disease is diabetes mellitus.