ADIPOQ and Sepsis: ZAGP has been suggested to be an adipokine that acts as a lipid-mobilizing factor playing a role in lipolysis [7]. Decreasing ZAGP levels are associated with the onset of lipotoxicity, which is supported by previous studies showing its positive association with adiponectin and negative association with tumor necrosis factor-alpha, suggesting a possible anti-inflammatory role of ZAGP [12,13]. This role was also found in a study in which ZAGP was reduced in early sepsis, and it increased with clinical recovery [14].