USP43 expression was higher in tumor tissues than in normal tissues in several types of tumors, including pancreatic adenocarcinoma (PAAD), rectum adenocarcinoma (READ), colon adenocarcinoma (COAD), cholangiocarcinoma (CHOL), stomach adenocarcinoma (STAD), and esophageal carcinoma (ESCA). This evidence concerns the gene USP43 and rectum adenocarcinoma.