IFNB1 and autoimmune disease: The most promising diquinothiazine, 6-chloroethylureidoethyldiquinothiazine, exerted suppressive and anti-inflammatory activities in the abovementioned in vivo models [43,44,45,46], and showed inhibitory activity of IFNβ expression and IFNβ-dependent downstream genes and proteins involved in the pathogenesis of autoimmune diseases [49].