The over-activation of STING is reported to be related to psoriasis, systemic lupus erythematosus (SLE), infectious diseases, non-alcoholic fatty liver disease (NAFLD), and other interferonopathies including STING-associated vasculopathy in infants (SAVI) and Aicardi–Goutières syndrome (AGS) [13,18,19,20]. This evidence concerns the gene STING1 and STING-associated vasculopathy with onset in infancy.