Neuroinflammation is a hallmark of neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), where it is prompted by the amyloid-β- and α-synuclein-induced activation of NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome, which promotes neurodegeneration [118,119]. Here, NLRP3 is linked to Alzheimer disease.