MCOLN1 and cancer: In a recent study, Qi et al. found that MCOLN1/TRPML1, which is a lysosomal non-selective cation channel, controlled the oncogenic autophagy process in cancer via the mechanism of regulating the influx of Zn ions into the cytoplasm [55], indicating the potential for determining the role exerted by Zn ions in the autophagic mechanism of cancer.