Moreover, we prudently excluded three SNPs, namely rs1260326 in GCKR, rs34894639 in PPP2R3A, and rs2943652 in NEU2, owing to their known pleiotropic effects on a range of human traits, including T2DM, coronary artery disease, BMI, and triglycerides, as evidenced by PhenoScanner database searches [12,13,43]. The gene discussed is GCKR; the disease is coronary artery disorder.