Maternal obesity: SCOPE women with obesity had lower PRL (−19%, [95% CI: 2 to 33%] p = 0.02), hPL (−21% [95% CI: 12 to 28%] p < 0.0001) and GH2 (−27%, [95% CI: 17 to 36%] p < 0.0001) compared to non-obese women (Table 6). The gene discussed is LGALS1; the disease is obesity due to melanocortin 4 receptor deficiency.