Platelet-coated PLGA nanoparticles overexpressing P-selectin were also used to deliver tumour-specific apoptosis-inducing ligand cytokine (TRAIL) and doxorubicin to MDA-MB-231 tumour cells in a murine animal model due to the specific binding of P-selectin to the CD44 receptors expressed on the tumour cells. Here, TNFSF10 is linked to neoplasm.