Perez-Belmonte et al. (2020) reported that the use of at-home metformin, insulin, DPP-4i, metformin plus insulin, and metformin plus SGLT-2 was significantly associated with in-hospital mortality, complications requiring ICU admission, mechanical ventilation, and longer hospitalization in COVID-19 patients with diabetes [30]. The gene discussed is INS; the disease is diabetes mellitus.