Leg radiculopathy (OR 2.902), leg weakness (OR 17.503), WBC (OR 1.159), CRP (OR 1.060), CCI (OR 1.283), identification of causative bacteria (OR 4.764), bacteremia (OR 5.042), extent of lesion (OR 1.356), epidural abscess (OR 2.692), and back muscle abscess (OR 2.377) in univariable analysis; and leg weakness (OR 15.966), WBC (OR 1.116), CCI (OR 1.283), and identification of causative bacteria (OR 4.764) in multivariable analysis; were statistically significant factors for the below-average initial SF-36. This evidence concerns the gene CRP and epidural abscess.