APOE and Alzheimer disease: Age at death, diuretic use, and APOE-e2 were the only characteristics independently associated with higher odds of the AD resilience phenotype (adjusted odds ratio with 95% CI: 1.09 (1.05–1.13); 2.00 (1.04–3.87); 2.71 (1.31–5.64), respectively) (Table 2).