The SLC7A11 mRNA is also stabilized by blocking its N6-methyladenosine (m6A) modification and YTHDF2-dependent degradation by suppressing methyltransferase like 14 (METTL14), which is a central component of the m6A methylated transferase complex, in a HIF-1α-dependent manner, to inhibit ferroptosis in hepatocellular carcinoma [106]. This evidence concerns the gene METTL14 and hepatocellular carcinoma.