SLC7A11 and preeclampsia: It was also found that the hypoxia (1% O2) increased miR-30b-5p to repress SLC7A11 and Pax3 (a transcription factor that promotes the expression of SLC7A11 and the iron exporter FPN1) levels, to induce ferroptosis of trophoblasts, leading to preeclampsia [130].