HIF1A and gastric cancer: Another study on the peritoneal metastasis of gastric cancer showed that 1% O2 hypoxia activates HIF-1α to transcriptionally induce lncRNA-PMAN expression via binding to the HRE sequence in its promotor, which recruits the embryonic lethal abnormal vision like RNA binding protein 1 (ELAVL1) to cytoplasm to stabilize SLC7A11 mRNA, thus leading to the inhibition of erastin- or RSL3-induced ferroptosis [105].