Particularly, mesenchymal cells are extracted based on the markers of various mesenchymal cells from all the lung cells (Supplementary Figure S3A–D) Based on known markers and expression of signature genes, these clusters are annotated as (a) UPK3B+ and CALB2+ mesothelial cells; (b) ACTA2+ smooth muscle cells (c) LUM+ and ACTA2+ Myofibroblasts, (d) DCN+ and LUM+ fibroblasts and (e) LUM+ PLA2G2A high “PLA2G2A IPF fibroblasts” (Supplementary Figure S4A–E). The gene discussed is CALB2; the disease is idiopathic pulmonary fibrosis.