COL14A1 and idiopathic pulmonary fibrosis: In addition to this, analysis of top 100 genes that are differentially regulated in PLA2G2A+ IPF fibroblasts has shown upregulation of multiple key extra cellular matrix (ECM) genes such FBLN1, COL1A2, COL1A1, MFAP5, FBN1, COL3A1, COL6A1, COL6A2 and COL14A1 (Figure 2G).