The pathway enrichment analysis revealed a significant upregulation of TGF-β signaling pathway, IL−17 signaling, arachidonic acid metabolism pathway, ECM-receptor interaction and other fibrosis-related pathways indicating the active role of PLA2G2A+ IPF fibroblasts in IPF (Figure 2F and Table 1). Here, PLA2G2A is linked to idiopathic pulmonary fibrosis.