Based on data from the CoMMpass, we identified 30 candidate genes, the regulation of expression of which may be related to KIAA: AC069499.1, MYH15, HNRNPR, KIF11, CENPI, USP1, CEP78, AMMECR1, RRM1, PLK4, TMPO, SMC4, SGO1, CEP55, BUB1, OSBPL11, KIF4A, CAPG, SPAG5, INCENP, POLA1, CDK1, ZWINT, SMC2, PCNA, SPATA5, NCAPG2, GPSM2, NCAPH and TOP2A. Disturbances in their expression have been the subject of many studies on the pathogenesis of solid tumors, e.g., lung, breast, endometrial, stomach and colon cancer [51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68]. The gene discussed is TOP2A; the disease is malignant colon neoplasm.