A research paper by Wang et al. [35] revealed that, with its N-terminal (amino acids 1–560), CIP2A could bind directly to the B56α and B56γ subunits of the PP2A protein—both of which are tumor suppressor units—and that the region necessary for this was located between the amino acids 159 and 245 and positively charged. This evidence concerns the gene PPP2R5C and neoplasm.