To verify whether Octa and A02 were able to interfere with the EMT process in cutaneous squamous cell carcinoma, A431 cells were pre-treated with the compounds for 1 h and then exposed to the EMT inductor TGF-β1 (15 ng/mL) [42] for 48 h. The gene discussed is TGFB1; the disease is cutaneous squamous cell carcinoma.