CS and Alzheimer disease: In mice treated with mitochondria from the age of 6 months (four IV injections), we detected an increase in the mitochondrial activity expressed as COX/CS ratio (COX normalized to CS activity) in the cortex and the liver in the mitochondria-treated AD mice compared to the untreated AD mice, reaching, and even exceeding, the activity of the non-AD mice, as follows: One-way ANOVA showed a significant difference in the brain between the groups [f(2, 11) = 8.064, p = 0.007].