A beneficial effect of the mitochondrial transfer was also evident in the liver: a higher COX/CS ratio was detected in the treated AD mice relative to the untreated AD mice (t-test, p = 0.004), reaching an even higher value than that in the liver of the non-AD mice, with a trend showing a reduced ratio in the AD relative to non-AD mice (p = 0.1) (Figure 3B). Here, CS is linked to Alzheimer disease.