It has also been reported to play a crucial role in the promotion of apoptotic cell death through inhibition of the epidermal growth factor receptor (EGFR), signal transducer and activator of transcription 3 (STAT3), and NF-κB transcription factor pathways in breast cancer cells and head and neck squamous cell carcinoma cells [192,193]. The gene discussed is STAT3; the disease is head and neck squamous cell carcinoma.