It has also been reported to play a crucial role in the promotion of apoptotic cell death through inhibition of the epidermal growth factor receptor (EGFR), signal transducer and activator of transcription 3 (STAT3), and NF-κB transcription factor pathways in breast cancer cells and head and neck squamous cell carcinoma cells [192,193]. This evidence concerns the gene STAT3 and breast carcinoma.