It is suggested that plasma levels of adiponectin be used as a biomarker for obesity [12] and there are few studies on the nature of adiponectin in saliva; a study by Toda et al. was the first to measure adiponectin in saliva after Groschl et al. suggested its existence [13,14]. Here, ADIPOQ is linked to obesity due to melanocortin 4 receptor deficiency.