TH and Alzheimer disease: Cu is a component of dopamine β-hydroxylase and MAO, and Fe of tyrosine hydroxylase, all involved in the catecholamine balance [40] that is altered in disorders of Cu metabolism, e.g., in Wilson disease, the paradigm of non-Cp Cu disbalance [35,41], and in a specific subtype of Alzheimer’s disease (AD), the main form of dementia in the elderly, namely, the ‘CuAD’ [42], typified by non-Cp Cu values higher than normal reference values (>1.6 μmol/L) [35,43].