CP and myocardial infarction: This dynamic resembles the Cu dynamics after Myocardial Infarction (MI) [71,72], demonstrating an 80% release of Cu from the damaged myocardial tissue caused by myocardial infarction and a subsequent uptake of Cu by the liver; the increase in serum ceruloplasmin at 3 days in response to myocardial infarction was the result of the increased Cu uptake of serum non-Cp Cu released from the damaged myocardium, rather than resulting from an inflammatory response.